000 01753 a2200529 4500
005 20250513075547.0
264 0 _c19931109
008 199311s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm00072a002
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMitch, C H
245 0 0 _a3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: opioid antagonists with potent anorectant activity.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cOct 1993
300 _a2842-50 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article
650 0 4 _aAnalgesia
650 0 4 _aAnimals
650 0 4 _aAppetite Depressants
_xchemistry
650 0 4 _aCyclohexanes
_xchemistry
650 0 4 _aDiuresis
_xdrug effects
650 0 4 _aEating
_xdrug effects
650 0 4 _aEndorphins
_xantagonists & inhibitors
650 0 4 _aGuinea Pigs
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMolecular Structure
650 0 4 _aPiperidines
_xchemistry
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aRats, Zucker
650 0 4 _aReceptors, Opioid, delta
_xantagonists & inhibitors
650 0 4 _aReceptors, Opioid, kappa
_xantagonists & inhibitors
650 0 4 _aReceptors, Opioid, mu
_xantagonists & inhibitors
650 0 4 _aStructure-Activity Relationship
700 1 _aLeander, J D
700 1 _aMendelsohn, L G
700 1 _aShaw, W N
700 1 _aWong, D T
700 1 _aCantrell, B E
700 1 _aJohnson, B G
700 1 _aReel, J K
700 1 _aSnoddy, J D
700 1 _aTakemori, A E
773 0 _tJournal of medicinal chemistry
_gvol. 36
_gno. 20
_gp. 2842-50
856 4 0 _uhttps://doi.org/10.1021/jm00072a002
_zAvailable from publisher's website
999 _c8410272
_d8410272