000			01830 a2200517 4500
005			20250513074750.0
264		0	_c19930609
008			199306s 0 0 eng d
022			_a0022-2623
024	7		_a10.1021/jm00061a005 _2doi
040			_aNLM _beng _cNLM
100	1		_aKuo, S C
245	0	0	_aSynthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. _h[electronic resource]
260			_bJournal of medicinal chemistry _cApr 1993
300			_a1146-56 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650	0	4	_aAnimals
650	0	4	_aAntineoplastic Agents _xchemical synthesis
650	0	4	_aHumans
650	0	4	_aIntestinal Neoplasms _xdrug therapy
650	0	4	_aLeukemia L1210 _xdrug therapy
650	0	4	_aLeukemia P388 _xdrug therapy
650	0	4	_aLung Neoplasms _xdrug therapy
650	0	4	_aMelanoma _xdrug therapy
650	0	4	_aMice
650	0	4	_aMolecular Structure
650	0	4	_aNasopharyngeal Neoplasms _xdrug therapy
650	0	4	_aQuinolines _xchemical synthesis
650	0	4	_aQuinolones _xchemical synthesis
650	0	4	_aSoftware
650	0	4	_aStructure-Activity Relationship
650	0	4	_aTubulin _xmetabolism
650	0	4	_aTubulin Modulators
650	0	4	_aTumor Cells, Cultured
700	1		_aLee, H Z
700	1		_aJuang, J P
700	1		_aLin, Y T
700	1		_aWu, T S
700	1		_aChang, J J
700	1		_aLednicer, D
700	1		_aPaull, K D
700	1		_aLin, C M
700	1		_aHamel, E
773	0		_tJournal of medicinal chemistry _gvol. 36 _gno. 9 _gp. 1146-56
856	4	0	_uhttps://doi.org/10.1021/jm00061a005 _zAvailable from publisher's website
999			_c8386869 _d8386869