000 01831 a2200493 4500
005 20250513073849.0
264 0 _c19930924
008 199309s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm00068a002
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSircar, I
245 0 0 _aNonpeptide angiotensin II receptor antagonists. 2. Design, synthesis, and structure-activity relationships of 2-alkyl-4-(1H-pyrrol-1-yl)-1H-imidazole derivatives: profile of 2-propyl-1-[[2'-(1H-tetrazol-5-yl)-[1,1' -biphenyl]-4-yl]-methyl]-4-[2-(trifluoroacetyl)-1H-pyrrol-1-yl]-1H- imidazole-5-carboxylic acid (CI-996).
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cAug 1993
300 _a2253-65 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAngiotensin Receptor Antagonists
650 0 4 _aAnimals
650 0 4 _aAorta
650 0 4 _aDisease Models, Animal
650 0 4 _aGABA Antagonists
650 0 4 _aHypertension, Renal
_xprevention & control
650 0 4 _aLiver
_xmetabolism
650 0 4 _aMale
650 0 4 _aMuscle Contraction
_xdrug effects
650 0 4 _aPyridines
_xadministration & dosage
650 0 4 _aRabbits
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aReceptors, Angiotensin
_xchemistry
650 0 4 _aStructure-Activity Relationship
650 0 4 _agamma-Aminobutyric Acid
_xadministration & dosage
700 1 _aHodges, J C
700 1 _aQuin, J
700 1 _aBunker, A M
700 1 _aWinters, R T
700 1 _aEdmunds, J J
700 1 _aKostlan, C R
700 1 _aConnolly, C
700 1 _aKesten, S J
700 1 _aHamby, J M
773 0 _tJournal of medicinal chemistry
_gvol. 36
_gno. 16
_gp. 2253-65
856 4 0 _uhttps://doi.org/10.1021/jm00068a002
_zAvailable from publisher's website
999 _c8360135
_d8360135