000 | 01540 a2200445 4500 | ||
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005 | 20250513072050.0 | ||
264 | 0 | _c19940315 | |
008 | 199403s 0 0 eng d | ||
022 | _a0022-2623 | ||
024 | 7 |
_a10.1021/jm00029a001 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aStein, P D | |
245 | 0 | 0 |
_aThe discovery of sulfonamide endothelin antagonists and the development of the orally active ETA antagonist 5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulf onamide. _h[electronic resource] |
260 |
_bJournal of medicinal chemistry _cFeb 1994 |
||
300 |
_a329-31 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAntihypertensive Agents _xchemical synthesis |
650 | 0 | 4 | _aCell Line |
650 | 0 | 4 |
_aDansyl Compounds _xchemical synthesis |
650 | 0 | 4 | _aEndothelin Receptor Antagonists |
650 | 0 | 4 |
_aEndothelins _xmetabolism |
650 | 0 | 4 |
_aHypertension _xdrug therapy |
650 | 0 | 4 | _aMolecular Structure |
650 | 0 | 4 |
_aMuscle, Smooth, Vascular _xdrug effects |
650 | 0 | 4 | _aRabbits |
650 | 0 | 4 | _aRats |
650 | 0 | 4 | _aStructure-Activity Relationship |
700 | 1 | _aHunt, J T | |
700 | 1 | _aFloyd, D M | |
700 | 1 | _aMoreland, S | |
700 | 1 | _aDickinson, K E | |
700 | 1 | _aMitchell, C | |
700 | 1 | _aLiu, E C | |
700 | 1 | _aWebb, M L | |
700 | 1 | _aMurugesan, N | |
700 | 1 | _aDickey, J | |
773 | 0 |
_tJournal of medicinal chemistry _gvol. 37 _gno. 3 _gp. 329-31 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm00029a001 _zAvailable from publisher's website |
999 |
_c8308137 _d8308137 |