000 01133 a2200313 4500
005 20250513062109.0
264 0 _c19940412
008 199404s 0 0 eng d
022 _a0021-9258
040 _aNLM
_beng
_cNLM
100 1 _aManchester, M
245 0 0 _aIdentification of temperature-sensitive mutants of the human immunodeficiency virus type 1 protease through saturation mutagenesis. Amino acid side chain requirements for temperature sensitivity.
_h[electronic resource]
260 _bThe Journal of biological chemistry
_cMar 1994
300 _a7689-95 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAmino Acids
_xmetabolism
650 0 4 _aEnzyme Stability
650 0 4 _aHIV Protease
_xgenetics
650 0 4 _aModels, Molecular
650 0 4 _aMutagenesis
650 0 4 _aPhenotype
650 0 4 _aProtein Conformation
650 0 4 _aTemperature
700 1 _aEveritt, L
700 1 _aLoeb, D D
700 1 _aHutchison, C A
700 1 _aSwanstrom, R
773 0 _tThe Journal of biological chemistry
_gvol. 269
_gno. 10
_gp. 7689-95
999 _c8125320
_d8125320