000			01440 a2200385 4500
005			20250513060902.0
264		0	_c19941018
008			199410s 0 0 eng d
022			_a0006-2960
024	7		_a10.1021/bi00202a024 _2doi
040			_aNLM _beng _cNLM
100	1		_aLaptev, A V
245	0	0	_aSpecific inhibition of expression of a human collagen gene (COL1A1) with modified antisense oligonucleotides. The most effective target sites are clustered in double-stranded regions of the predicted secondary structure for the mRNA. _h[electronic resource]
260			_bBiochemistry _cSep 1994
300			_a11033-9 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650	0	4	_a3T3 Cells
650	0	4	_aAnimals
650	0	4	_aBase Sequence
650	0	4	_aBinding Sites
650	0	4	_aCollagen _xgenetics
650	0	4	_aDNA Primers
650	0	4	_aGene Expression Regulation _xdrug effects
650	0	4	_aHumans
650	0	4	_aMice
650	0	4	_aMolecular Sequence Data
650	0	4	_aNucleic Acid Conformation
650	0	4	_aOligonucleotides, Antisense _xpharmacology
650	0	4	_aRNA, Messenger _xchemistry
700	1		_aLu, Z
700	1		_aColige, A
700	1		_aProckop, D J
773	0		_tBiochemistry _gvol. 33 _gno. 36 _gp. 11033-9
856	4	0	_uhttps://doi.org/10.1021/bi00202a024 _zAvailable from publisher's website
999			_c8085744 _d8085744