000 01454 a2200385 4500
005 20250513060449.0
264 0 _c19940928
008 199409s 0 0 eng d
022 _a0022-3565
040 _aNLM
_beng
_cNLM
100 1 _aMurray, M
245 0 0 _aCompetitive inhibition of human liver microsomal cytochrome P450 3A-dependent steroid 6 beta-hydroxylation activity by cyclophosphamide and ifosfamide in vitro.
_h[electronic resource]
260 _bThe Journal of pharmacology and experimental therapeutics
_cAug 1994
300 _a645-9 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAcrolein
_xmetabolism
650 0 4 _aAnimals
650 0 4 _aBinding, Competitive
650 0 4 _aCyclophosphamide
_xpharmacology
650 0 4 _aCytochrome P-450 CYP2E1
650 0 4 _aCytochrome P-450 Enzyme Inhibitors
650 0 4 _aCytochrome P-450 Enzyme System
_xmetabolism
650 0 4 _aHumans
650 0 4 _aIfosfamide
_xpharmacology
650 0 4 _aMicrosomes, Liver
_xdrug effects
650 0 4 _aMixed Function Oxygenases
_xantagonists & inhibitors
650 0 4 _aNADP
_xmetabolism
650 0 4 _aRats
650 0 4 _aRats, Wistar
650 0 4 _aSteroid Hydroxylases
_xmetabolism
650 0 4 _aTestosterone
_xmetabolism
700 1 _aButler, A M
700 1 _aStupans, I
773 0 _tThe Journal of pharmacology and experimental therapeutics
_gvol. 270
_gno. 2
_gp. 645-9
999 _c8071182
_d8071182