000 01510 a2200409 4500
005 20250513054850.0
264 0 _c19940803
008 199408s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm00038a010
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aO'Brien, P M
245 0 0 _aInhibitors of acyl-CoA:cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. 8. Incorporation of amide or amine functionalities into a series of disubstituted ureas and carbamates. Effects on ACAT inhibition in vitro and efficacy in vivo.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cJun 1994
300 _a1810-22 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAmides
_xchemistry
650 0 4 _aAmines
_xchemistry
650 0 4 _aAnimals
650 0 4 _aAnticholesteremic Agents
_xchemistry
650 0 4 _aCarbamates
_xchemistry
650 0 4 _aDisease Models, Animal
650 0 4 _aRabbits
650 0 4 _aRats
650 0 4 _aSterol O-Acyltransferase
_xantagonists & inhibitors
650 0 4 _aStructure-Activity Relationship
650 0 4 _aUrea
_xchemistry
700 1 _aSliskovic, D R
700 1 _aBlankley, C J
700 1 _aRoth, B D
700 1 _aWilson, M W
700 1 _aHamelehle, K L
700 1 _aKrause, B R
700 1 _aStanfield, R L
773 0 _tJournal of medicinal chemistry
_gvol. 37
_gno. 12
_gp. 1810-22
856 4 0 _uhttps://doi.org/10.1021/jm00038a010
_zAvailable from publisher's website
999 _c8021249
_d8021249