000 01367 a2200421 4500
005 20250513052449.0
264 0 _c19941216
008 199412s 0 0 eng d
022 _a0266-9536
040 _aNLM
_beng
_cNLM
100 1 _aArris, C E
245 0 0 _aProbing the active site and mechanism of action of O6-methylguanine-DNA methyltransferase with substrate analogues (O6-substituted guanines).
_h[electronic resource]
260 _bAnti-cancer drug design
_cOct 1994
300 _a401-8 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAmino Acid Sequence
650 0 4 _aAnimals
650 0 4 _aBinding Sites
_xdrug effects
650 0 4 _aCattle
650 0 4 _aColorectal Neoplasms
_xenzymology
650 0 4 _aEnzyme Activation
_xdrug effects
650 0 4 _aGuanine
_xanalogs & derivatives
650 0 4 _aHumans
650 0 4 _aMethyltransferases
_xdrug effects
650 0 4 _aMolecular Sequence Data
650 0 4 _aO(6)-Methylguanine-DNA Methyltransferase
650 0 4 _aStructure-Activity Relationship
700 1 _aBleasdale, C
700 1 _aCalvert, A H
700 1 _aCurtin, N J
700 1 _aDalby, C
700 1 _aGolding, B T
700 1 _aGriffin, R J
700 1 _aLunn, J M
700 1 _aMajor, G N
700 1 _aNewell, D R
773 0 _tAnti-cancer drug design
_gvol. 9
_gno. 5
_gp. 401-8
999 _c7945044
_d7945044