000			01955 a2200517 4500
005			20250513052100.0
264		0	_c19941103
008			199411s 0 0 eng d
022			_a0022-2623
024	7		_a10.1021/jm00046a021 _2doi
040			_aNLM _beng _cNLM
100	1		_aMinarini, A
245	0	0	_aDesign, synthesis, and biological activity of methoctramine-related tetraamines bearing an 11-acetyl-5,11-dihydro-6H-pyrido[2,3-b][1,4] benzodiazepin-6-one moiety: structural requirements for optimum occupancy of muscarinic receptor subtypes as revealed by symmetrical and unsymmetrical polyamines. _h[electronic resource]
260			_bJournal of medicinal chemistry _cSep 1994
300			_a3363-72 p. _bdigital
500			_aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aAtrial Function
650	0	4	_aBenzodiazepines _xchemical synthesis
650	0	4	_aCells, Cultured
650	0	4	_aCerebral Cortex _xmetabolism
650	0	4	_aDrug Design
650	0	4	_aFemale
650	0	4	_aGuinea Pigs
650	0	4	_aHeart Atria _xdrug effects
650	0	4	_aIleum _xdrug effects
650	0	4	_aMale
650	0	4	_aMolecular Structure
650	0	4	_aMuscarinic Antagonists
650	0	4	_aMuscle Contraction _xdrug effects
650	0	4	_aMyocardial Contraction _xdrug effects
650	0	4	_aMyocardium _xmetabolism
650	0	4	_aPolyamines _xchemical synthesis
650	0	4	_aRats
650	0	4	_aReceptors, Muscarinic _xmetabolism
650	0	4	_aStructure-Activity Relationship
650	0	4	_aSubmandibular Gland _xmetabolism
700	1		_aBolognesi, M L
700	1		_aBudriesi, R
700	1		_aCanossa, M
700	1		_aChiarini, A
700	1		_aSpampinato, S
700	1		_aMelchiorre, C
773	0		_tJournal of medicinal chemistry _gvol. 37 _gno. 20 _gp. 3363-72
856	4	0	_uhttps://doi.org/10.1021/jm00046a021 _zAvailable from publisher's website
999			_c7931894 _d7931894