000 01492 a2200385 4500
005 20250513050814.0
264 0 _c19950414
008 199504s 0 0 eng d
022 _a0022-3565
040 _aNLM
_beng
_cNLM
100 1 _aJoseph, D B
245 0 0 _aThe kappa opioid receptor expressed on the mouse R1.1 thymoma cell line down-regulates without desensitizing during chronic opioid exposure.
_h[electronic resource]
260 _bThe Journal of pharmacology and experimental therapeutics
_cMar 1995
300 _a970-6 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _a3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer
650 0 4 _aAdenylate Cyclase Toxin
650 0 4 _aAdenylyl Cyclases
_xmetabolism
650 0 4 _aAnimals
650 0 4 _aBenzeneacetamides
650 0 4 _aCell Membrane
_xmetabolism
650 0 4 _aDown-Regulation
650 0 4 _aIn Vitro Techniques
650 0 4 _aMice
650 0 4 _aNaloxone
_xmetabolism
650 0 4 _aNaltrexone
_xanalogs & derivatives
650 0 4 _aPertussis Toxin
650 0 4 _aPyrrolidines
_xadministration & dosage
650 0 4 _aReceptors, Opioid, kappa
_xagonists
650 0 4 _aThymoma
650 0 4 _aTumor Cells, Cultured
650 0 4 _aVirulence Factors, Bordetella
_xpharmacology
700 1 _aBidlack, J M
773 0 _tThe Journal of pharmacology and experimental therapeutics
_gvol. 272
_gno. 3
_gp. 970-6
999 _c7890685
_d7890685