000 02030 a2200553 4500
005 20250513050813.0
264 0 _c19950414
008 199504s 0 0 eng d
022 _a0022-3565
040 _aNLM
_beng
_cNLM
100 1 _aHancock, A A
245 0 0 _aPreclinical pharmacological actions of (+/-)-(1'R*,3R*)-3-phenyl-1- [1',2',3',4'-tetrahydro-5',6'-methylene-dioxy-1'-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200), a potential antidepressant agent that antagonizes alpha-2 adrenergic receptors and inhibits the neuronal uptake of norepinephrine.
_h[electronic resource]
260 _bThe Journal of pharmacology and experimental therapeutics
_cMar 1995
300 _a1160-9 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdrenergic Uptake Inhibitors
_xpharmacology
650 0 4 _aAdrenergic alpha-2 Receptor Antagonists
650 0 4 _aAnimals
650 0 4 _aAntidepressive Agents
_xpharmacology
650 0 4 _aBehavior, Animal
_xdrug effects
650 0 4 _aBlood Pressure
_xdrug effects
650 0 4 _aClonidine
_xpharmacology
650 0 4 _aGuinea Pigs
650 0 4 _aHeart Rate
_xdrug effects
650 0 4 _aHippocampus
_xmetabolism
650 0 4 _aIn Vitro Techniques
650 0 4 _aMale
650 0 4 _aMotor Activity
_xdrug effects
650 0 4 _aMydriasis
_xchemically induced
650 0 4 _aNeurons
_xmetabolism
650 0 4 _aOlfactory Bulb
_xphysiology
650 0 4 _aPyrrolidines
_xpharmacology
650 0 4 _aRabbits
650 0 4 _aRadioligand Assay
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aSynaptosomes
_xmetabolism
650 0 4 _aTyramine
_xanalogs & derivatives
700 1 _aBuckner, S A
700 1 _aGiardina, W J
700 1 _aBrune, M E
700 1 _aLee, J Y
700 1 _aMorse, P A
700 1 _aOheim, K W
700 1 _aStanisic, D S
700 1 _aWarner, R B
700 1 _aKerkman, D J
773 0 _tThe Journal of pharmacology and experimental therapeutics
_gvol. 272
_gno. 3
_gp. 1160-9
999 _c7890661
_d7890661