000 01445 a2200397 4500
005 20250513044848.0
264 0 _c19950223
008 199502s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm00002a002
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDolle, R E
245 0 0 _aAspartyl alpha-((diphenylphosphinyl)oxy)methyl ketones as novel inhibitors of interleukin-1 beta converting enzyme. Utility of the diphenylphosphinic acid leaving group for the inhibition of cysteine proteases.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cJan 1995
300 _a220-2 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAspartic Acid
_xchemistry
650 0 4 _aCalpain
_xantagonists & inhibitors
650 0 4 _aCaspase 1
650 0 4 _aCathepsin B
_xantagonists & inhibitors
650 0 4 _aCysteine Endopeptidases
_xmetabolism
650 0 4 _aCysteine Proteinase Inhibitors
650 0 4 _aKetones
_xchemistry
650 0 4 _aStructure-Activity Relationship
700 1 _aSingh, J
700 1 _aWhipple, D
700 1 _aOsifo, I K
700 1 _aSpeier, G
700 1 _aGraybill, T L
700 1 _aGregory, J S
700 1 _aHarris, A L
700 1 _aHelaszek, C T
700 1 _aMiller, R E
773 0 _tJournal of medicinal chemistry
_gvol. 38
_gno. 2
_gp. 220-2
856 4 0 _uhttps://doi.org/10.1021/jm00002a002
_zAvailable from publisher's website
999 _c7829607
_d7829607