000 01713 a2200457 4500
005 20250513044137.0
264 0 _c19950130
008 199501s 0 0 eng d
022 _a0021-9258
040 _aNLM
_beng
_cNLM
100 1 _aOuwens, D M
245 0 0 _aA mutant insulin receptor induces formation of a Shc-growth factor receptor bound protein 2 (Grb2) complex and p21ras-GTP without detectable interaction of insulin receptor substrate 1 (IRS1) with Grb2. Evidence for IRS1-independent p21ras-GTP formation.
_h[electronic resource]
260 _bThe Journal of biological chemistry
_cDec 1994
300 _a33116-22 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdaptor Proteins, Signal Transducing
650 0 4 _aAnimals
650 0 4 _aCHO Cells
650 0 4 _aCricetinae
650 0 4 _aGRB2 Adaptor Protein
650 0 4 _aGuanosine Triphosphate
_xmetabolism
650 0 4 _aInsulin Receptor Substrate Proteins
650 0 4 _aMitogen-Activated Protein Kinase 1
650 0 4 _aMutation
650 0 4 _aOncogene Protein p21(ras)
_xmetabolism
650 0 4 _aPhosphoproteins
_xmetabolism
650 0 4 _aPhosphorylation
650 0 4 _aProtein Serine-Threonine Kinases
_xmetabolism
650 0 4 _aProtein-Tyrosine Kinases
_xmetabolism
650 0 4 _aProteins
_xmetabolism
650 0 4 _aReceptor, Insulin
_xgenetics
650 0 4 _aTyrosine
_xmetabolism
700 1 _avan der Zon, G C
700 1 _aPronk, G J
700 1 _aBos, J L
700 1 _aMöller, W
700 1 _aCheatham, B
700 1 _aKahn, C R
700 1 _aMaassen, J A
773 0 _tThe Journal of biological chemistry
_gvol. 269
_gno. 52
_gp. 33116-22
999 _c7805897
_d7805897