000 01784 a2200469 4500
005 20250513040607.0
264 0 _c19931208
008 199312s 0 0 eng d
022 _a0269-2139
024 7 _a10.1093/protein/6.6.661
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aRuff-Jamison, S
245 0 0 _aMolecular modeling and site-directed mutagenesis of an anti-phosphotyrosine antibody predicts the combining site and allows the detection of higher affinity interactions.
_h[electronic resource]
260 _bProtein engineering
_cAug 1993
300 _a661-8 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article
650 0 4 _aAmino Acid Sequence
650 0 4 _aAntibodies, Monoclonal
_xchemistry
650 0 4 _aAntigen-Antibody Reactions
650 0 4 _aBinding Sites, Antibody
650 0 4 _aBlotting, Western
650 0 4 _aComputer Simulation
650 0 4 _aCrystallography, X-Ray
650 0 4 _aEnzyme-Linked Immunosorbent Assay
650 0 4 _aImmunoglobulin Fab Fragments
_xchemistry
650 0 4 _aImmunoglobulin Heavy Chains
_xchemistry
650 0 4 _aImmunoglobulin Light Chains
_xchemistry
650 0 4 _aImmunoglobulin Variable Region
_xchemistry
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Sequence Data
650 0 4 _aMutagenesis, Site-Directed
650 0 4 _aPhosphotyrosine
650 0 4 _aPolymerase Chain Reaction
650 0 4 _aProtein Conformation
650 0 4 _aSequence Alignment
650 0 4 _aSequence Homology, Amino Acid
650 0 4 _aTemplates, Genetic
650 0 4 _aTyrosine
_xanalogs & derivatives
700 1 _aGlenney, J R
773 0 _tProtein engineering
_gvol. 6
_gno. 6
_gp. 661-8
856 4 0 _uhttps://doi.org/10.1093/protein/6.6.661
_zAvailable from publisher's website
999 _c7693690
_d7693690