000 01532 a2200433 4500
005 20250513034459.0
264 0 _c19950905
008 199509s 0 0 eng d
022 _a0006-2960
024 7 _a10.1021/bi00030a003
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTrzaskos, J M
245 0 0 _aSubstrate-based inhibitors of lanosterol 14 alpha-methyl demethylase: I. Assessment of inhibitor structure-activity relationship and cholesterol biosynthesis inhibition properties.
_h[electronic resource]
260 _bBiochemistry
_cAug 1995
300 _a9670-6 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article
650 0 4 _aAnimals
650 0 4 _aCHO Cells
650 0 4 _aCells, Cultured
650 0 4 _aCholesterol
_xbiosynthesis
650 0 4 _aCricetinae
650 0 4 _aCytochrome P-450 Enzyme Inhibitors
650 0 4 _aHydroxymethylglutaryl-CoA Reductase Inhibitors
650 0 4 _aLanosterol
_xanalogs & derivatives
650 0 4 _aMolecular Structure
650 0 4 _aOxidoreductases
_xantagonists & inhibitors
650 0 4 _aReceptors, LDL
_xmetabolism
650 0 4 _aSterol 14-Demethylase
650 0 4 _aStructure-Activity Relationship
700 1 _aKo, S S
700 1 _aMagolda, R L
700 1 _aFavata, M F
700 1 _aFischer, R T
700 1 _aStam, S H
700 1 _aJohnson, P R
700 1 _aGaylor, J L
773 0 _tBiochemistry
_gvol. 34
_gno. 30
_gp. 9670-6
856 4 0 _uhttps://doi.org/10.1021/bi00030a003
_zAvailable from publisher's website
999 _c7626072
_d7626072