000 01227 a2200349 4500
005 20250513015926.0
264 0 _c19811215
008 198112s 0 0 eng d
022 _a0021-9258
040 _aNLM
_beng
_cNLM
100 1 _aHaber, D A
245 0 0 _aProperties of an altered dihydrofolate reductase encoded by amplified genes in cultured mouse fibroblasts.
_h[electronic resource]
260 _bThe Journal of biological chemistry
_cSep 1981
300 _a9501-10 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAnimals
650 0 4 _aCell Line
650 0 4 _aDrug Stability
650 0 4 _aEmbryo, Mammalian
650 0 4 _aFibroblasts
_xenzymology
650 0 4 _aFolic Acid Antagonists
_xpharmacology
650 0 4 _aGene Amplification
_xdrug effects
650 0 4 _aHydrogen-Ion Concentration
650 0 4 _aKinetics
650 0 4 _aMethotrexate
_xmetabolism
650 0 4 _aMice
650 0 4 _aTetrahydrofolate Dehydrogenase
_xgenetics
700 1 _aBeverley, S M
700 1 _aKiely, M L
700 1 _aSchimke, R T
773 0 _tThe Journal of biological chemistry
_gvol. 256
_gno. 18
_gp. 9501-10
999 _c7287211
_d7287211