| 000 | 01094 a2200313 4500 | ||
|---|---|---|---|
| 005 | 20250513003521.0 | ||
| 264 | 0 | _c19810421 | |
| 008 | 198104s 0 0 eng d | ||
| 022 | _a0021-9258 | ||
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aBaccanari, D P | |
| 245 | 0 | 0 |
_aEffect of a single amino acid substitution on Escherichia coli dihydrofolate reductase catalysis and ligand binding. _h[electronic resource] |
| 260 |
_bThe Journal of biological chemistry _cFeb 1981 |
||
| 300 |
_a1738-47 p. _bdigital |
||
| 500 | _aPublication Type: Comparative Study; Journal Article | ||
| 650 | 0 | 4 | _aAmino Acid Sequence |
| 650 | 0 | 4 |
_aAmino Acids _xanalysis |
| 650 | 0 | 4 | _aDrug Resistance, Microbial |
| 650 | 0 | 4 |
_aEscherichia coli _xdrug effects |
| 650 | 0 | 4 |
_aIsoenzymes _xmetabolism |
| 650 | 0 | 4 | _aKinetics |
| 650 | 0 | 4 | _aLigands |
| 650 | 0 | 4 | _aProtein Binding |
| 650 | 0 | 4 |
_aTetrahydrofolate Dehydrogenase _xmetabolism |
| 650 | 0 | 4 |
_aTrimethoprim _xpharmacology |
| 700 | 1 | _aStone, D | |
| 700 | 1 | _aKuyper, L | |
| 773 | 0 |
_tThe Journal of biological chemistry _gvol. 256 _gno. 4 _gp. 1738-47 |
|
| 999 |
_c7007030 _d7007030 |
||