000			01784 a2200445 4500
005			20250512211926.0
264		0	_c19840820
008			198408s 0 0 eng d
022			_a0277-3732
040			_aNLM _beng _cNLM
100	1		_aEngstrom, P F
245	0	0	_aChemotherapy of advanced colorectal carcinoma: fluorouracil alone vs. two drug combinations using fluorouracil, hydroxyurea, semustine, dacarbazine, razoxane, and mitomycin. A phase III trial by the Eastern Cooperative Oncology Group (EST: 1278). _h[electronic resource]
260			_bAmerican journal of clinical oncology _cAug 1984
300			_a313-8 p. _bdigital
500			_aPublication Type: Clinical Trial; Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
650	0	4	_aAdenocarcinoma _xdrug therapy
650	0	4	_aAntineoplastic Combined Chemotherapy Protocols _xadverse effects
650	0	4	_aClinical Trials as Topic
650	0	4	_aColonic Neoplasms _xdrug therapy
650	0	4	_aDacarbazine _xtherapeutic use
650	0	4	_aDrug Administration Schedule
650	0	4	_aFemale
650	0	4	_aFluorouracil _xadministration & dosage
650	0	4	_aGastrointestinal Diseases _xchemically induced
650	0	4	_aHematologic Diseases _xchemically induced
650	0	4	_aHumans
650	0	4	_aHydroxyurea _xtherapeutic use
650	0	4	_aMale
650	0	4	_aMiddle Aged
650	0	4	_aMitomycins _xtherapeutic use
650	0	4	_aRandom Allocation
650	0	4	_aRazoxane _xtherapeutic use
650	0	4	_aRectal Neoplasms _xdrug therapy
650	0	4	_aSemustine _xtherapeutic use
650	0	4	_aTime Factors
700	1		_aMacIntyre, J M
700	1		_aMittelman, A
700	1		_aKlaassen, D J
773	0		_tAmerican journal of clinical oncology _gvol. 7 _gno. 4 _gp. 313-8
999			_c6377779 _d6377779