| 000 | 01294 a2200385 4500 | ||
|---|---|---|---|
| 005 | 20250512211220.0 | ||
| 264 | 0 | _c19831217 | |
| 008 | 198312s 0 0 eng d | ||
| 022 | _a0036-8075 | ||
| 024 | 7 |
_a10.1126/science.6356360 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aVillafranca, J E | |
| 245 | 0 | 0 |
_aDirected mutagenesis of dihydrofolate reductase. _h[electronic resource] |
| 260 |
_bScience (New York, N.Y.) _cNov 1983 |
||
| 300 |
_a782-8 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. | ||
| 650 | 0 | 4 | _aAmino Acid Sequence |
| 650 | 0 | 4 | _aBase Sequence |
| 650 | 0 | 4 | _aDisulfides |
| 650 | 0 | 4 |
_aEscherichia coli _xgenetics |
| 650 | 0 | 4 | _aGene Expression Regulation |
| 650 | 0 | 4 | _aGenes |
| 650 | 0 | 4 | _aGenes, Bacterial |
| 650 | 0 | 4 | _aMutation |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 650 | 0 | 4 |
_aTetrahydrofolate Dehydrogenase _xgenetics |
| 700 | 1 | _aHowell, E E | |
| 700 | 1 | _aVoet, D H | |
| 700 | 1 | _aStrobel, M S | |
| 700 | 1 | _aOgden, R C | |
| 700 | 1 | _aAbelson, J N | |
| 700 | 1 | _aKraut, J | |
| 773 | 0 |
_tScience (New York, N.Y.) _gvol. 222 _gno. 4625 _gp. 782-8 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1126/science.6356360 _zAvailable from publisher's website |
| 999 |
_c6356278 _d6356278 |
||