| 000 | 01225 a2200325 4500 | ||
|---|---|---|---|
| 005 | 20250512152303.0 | ||
| 264 | 0 | _c19690725 | |
| 008 | 196907s 0 0 eng d | ||
| 022 | _a0022-2623 | ||
| 024 | 7 |
_a10.1021/jm00302a007 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aBaker, B R | |
| 245 | 0 | 0 |
_aIrrevesible enzyme inhibitors. CLI. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 5-(p-aminophenylbutyl)-2,4-diaminopyrimidines with a terminal sulfonyl fluoride. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cMar 1969 |
||
| 300 |
_a224-7 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aBinding Sites |
| 650 | 0 | 4 |
_aFluorides _xchemical synthesis |
| 650 | 0 | 4 | _aFolic Acid Antagonists |
| 650 | 0 | 4 | _aIn Vitro Techniques |
| 650 | 0 | 4 |
_aLeukemia L1210 _xenzymology |
| 650 | 0 | 4 |
_aLiver _xenzymology |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 |
_aPyrimidines _xchemical synthesis |
| 650 | 0 | 4 |
_aSulfones _xchemical synthesis |
| 700 | 1 | _aMeyer, R B | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 12 _gno. 2 _gp. 224-7 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm00302a007 _zAvailable from publisher's website |
| 999 |
_c5255874 _d5255874 |
||