000 01867 a2200529 4500
005 20250512085354.0
264 0 _c19851227
008 198512s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm00149a025
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMacDiarmid, J E
245 0 0 _aSynthesis and properties of bis(2,2-dimethylaziridinyl)phosphinic amides: a series of new antineoplastic agents.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cNov 1985
300 _a1685-91 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAnimals
650 0 4 _aAziridines
_xchemical synthesis
650 0 4 _aAzirines
_xtherapeutic use
650 0 4 _aChemical Phenomena
650 0 4 _aChemistry
650 0 4 _aChlorambucil
_xtherapeutic use
650 0 4 _aCholinesterase Inhibitors
_xpharmacology
650 0 4 _aColonic Neoplasms
_xdrug therapy
650 0 4 _aCyclophosphamide
_xtherapeutic use
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aFemale
650 0 4 _aHydrolysis
650 0 4 _aKinetics
650 0 4 _aLeukemia L1210
_xdrug therapy
650 0 4 _aLeukemia P388
_xdrug therapy
650 0 4 _aMale
650 0 4 _aMelanoma
_xdrug therapy
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aMice, Inbred DBA
650 0 4 _aNeoplasms, Experimental
_xdrug therapy
650 0 4 _aOrganophosphorus Compounds
_xchemical synthesis
700 1 _aRose, W C
700 1 _aBiddle, W C
700 1 _aPerlman, M E
700 1 _aBreiner, R G
700 1 _aAmbrus, J L
700 1 _aBardos, T J
773 0 _tJournal of medicinal chemistry
_gvol. 28
_gno. 11
_gp. 1685-91
856 4 0 _uhttps://doi.org/10.1021/jm00149a025
_zAvailable from publisher's website
999 _c4073679
_d4073679