000 01766 a2200493 4500
005 20250512085304.0
264 0 _c19860116
008 198601s 0 0 eng d
022 _a0277-5379
024 7 _a10.1016/0277-5379(85)90298-6
_2doi
040 _aNLM
_beng
_cNLM
100 1 _avan Maanen, J M
245 0 0 _aThe role of metabolic activation by cytochrome P-450 in covalent binding of VP 16-213 to rat liver and HeLa cell microsomal proteins.
_h[electronic resource]
260 _bEuropean journal of cancer & clinical oncology
_cSep 1985
300 _a1099-106 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAscorbic Acid
_xpharmacology
650 0 4 _aBiotransformation
_xdrug effects
650 0 4 _aCytochrome P-450 Enzyme System
_xpharmacology
650 0 4 _aEtoposide
_xmetabolism
650 0 4 _aHeLa Cells
_xmetabolism
650 0 4 _aHumans
650 0 4 _aIn Vitro Techniques
650 0 4 _aMicrosomes
_xmetabolism
650 0 4 _aMicrosomes, Liver
_xmetabolism
650 0 4 _aNADP
650 0 4 _aNeoplasm Proteins
_xmetabolism
650 0 4 _aNitrogen Oxides
_xpharmacology
650 0 4 _aPhenobarbital
_xpharmacology
650 0 4 _aPodophyllotoxin
_xanalogs & derivatives
650 0 4 _aProadifen
_xpharmacology
650 0 4 _aProtein Binding
650 0 4 _aPyridines
650 0 4 _aRats
650 0 4 _aRats, Inbred Strains
700 1 _ade Ruiter, C
700 1 _ade Vries, J
700 1 _aKootstra, P R
700 1 _aGobas, F
700 1 _aPinedo, H M
773 0 _tEuropean journal of cancer & clinical oncology
_gvol. 21
_gno. 9
_gp. 1099-106
856 4 0 _uhttps://doi.org/10.1016/0277-5379(85)90298-6
_zAvailable from publisher's website
999 _c4070864
_d4070864