000			02144 a2200529 4500
005			20250512070511.0
264		0	_c19860917
008			198609s 0 0 eng d
022			_a0732-183X
024	7		_a10.1200/JCO.1986.4.8.1245 _2doi
040			_aNLM _beng _cNLM
100	1		_aCalvert, A H
245	0	0	_aA phase I evaluation of the quinazoline antifolate thymidylate synthase inhibitor, N10-propargyl-5,8-dideazafolic acid, CB3717. _h[electronic resource]
260			_bJournal of clinical oncology : official journal of the American Society of Clinical Oncology _cAug 1986
300			_a1245-52 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAcetylglucosaminidase _xurine
650	0	4	_aAcid Phosphatase _xblood
650	0	4	_aAlanine Transaminase _xblood
650	0	4	_aAntineoplastic Agents _xadministration & dosage
650	0	4	_aChemical and Drug Induced Liver Injury
650	0	4	_aDose-Response Relationship, Drug
650	0	4	_aDrug Administration Schedule
650	0	4	_aDrug Evaluation
650	0	4	_aFolic Acid _xanalogs & derivatives
650	0	4	_aFolic Acid Antagonists _xadministration & dosage
650	0	4	_aGlomerular Filtration Rate _xdrug effects
650	0	4	_aHematologic Diseases _xchemically induced
650	0	4	_aHyperbilirubinemia _xchemically induced
650	0	4	_aKidney Diseases _xchemically induced
650	0	4	_aLeucyl Aminopeptidase _xurine
650	0	4	_aNeoplasms _xblood
650	0	4	_aQuinazolines _xadministration & dosage
650	0	4	_aSkin Diseases _xchemically induced
650	0	4	_aThymidylate Synthase _xantagonists & inhibitors
700	1		_aAlison, D L
700	1		_aHarland, S J
700	1		_aRobinson, B A
700	1		_aJackman, A L
700	1		_aJones, T R
700	1		_aNewell, D R
700	1		_aSiddik, Z H
700	1		_aWiltshaw, E
700	1		_aMcElwain, T J
773	0		_tJournal of clinical oncology : official journal of the American Society of Clinical Oncology _gvol. 4 _gno. 8 _gp. 1245-52
856	4	0	_uhttps://doi.org/10.1200/JCO.1986.4.8.1245 _zAvailable from publisher's website
999			_c3740551 _d3740551