000 01175 a2200301 4500
005 20250512064701.0
264 0 _c19880111
008 198801s 0 0 eng d
022 _a0091-2700
024 7 _a10.1002/j.1552-4604.1987.tb03022.x
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBrowne, T R
245 0 0 _aEstimation of the elimination half-life of a drug at any serum concentration when the Km and Vmax of the drug are known: calculations and validation with phenytoin.
_h[electronic resource]
260 _bJournal of clinical pharmacology
_cApr 1987
300 _a318-20 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aHalf-Life
650 0 4 _aHumans
650 0 4 _aModels, Biological
650 0 4 _aPhenytoin
_xblood
700 1 _aGreenblatt, D J
700 1 _aEvans, J E
700 1 _aSzabo, G K
700 1 _aEvans, B A
700 1 _aSchumacher, G E
773 0 _tJournal of clinical pharmacology
_gvol. 27
_gno. 4
_gp. 318-20
856 4 0 _uhttps://doi.org/10.1002/j.1552-4604.1987.tb03022.x
_zAvailable from publisher's website
999 _c3686291
_d3686291