000 01211 a2200349 4500
005 20250512061716.0
264 0 _c19870630
008 198706s 0 0 eng d
022 _a0028-0836
024 7 _a10.1038/327434a0
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMaurer, B J
245 0 0 _aNovel submicroscopic extrachromosomal elements containing amplified genes in human cells.
_h[electronic resource]
260 _bNature
_c
300 _a434-7 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aDrug Resistance
650 0 4 _aExtrachromosomal Inheritance
650 0 4 _aGene Amplification
650 0 4 _aGenes
650 0 4 _aGenetic Variation
650 0 4 _aHeLa Cells
_xenzymology
650 0 4 _aHumans
650 0 4 _aMethotrexate
_xpharmacology
650 0 4 _aTetrahydrofolate Dehydrogenase
_xgenetics
700 1 _aLai, E
700 1 _aHamkalo, B A
700 1 _aHood, L
700 1 _aAttardi, G
773 0 _tNature
_gvol. 327
_gno. 6121
_gp. 434-7
856 4 0 _uhttps://doi.org/10.1038/327434a0
_zAvailable from publisher's website
999 _c3593082
_d3593082