000 01333 a2200361 4500
005 20250512045404.0
264 0 _c19880314
008 198803s 0 0 eng d
022 _a0166-6851
024 7 _a10.1016/0166-6851(87)90136-8
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aInselburg, J
245 0 0 _aPyrimethamine resistant Plasmodium falciparum: overproduction of dihydrofolate reductase by a gene duplication.
_h[electronic resource]
260 _bMolecular and biochemical parasitology
_cNov 1987
300 _a121-34 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAnimals
650 0 4 _aChromatography, Gel
650 0 4 _aDNA
_xgenetics
650 0 4 _aDrug Resistance
650 0 4 _aElectrophoresis, Polyacrylamide Gel
650 0 4 _aMultigene Family
650 0 4 _aMutation
650 0 4 _aNucleic Acid Hybridization
650 0 4 _aPlasmodium falciparum
_xdrug effects
650 0 4 _aPyrimethamine
_xpharmacology
650 0 4 _aTetrahydrofolate Dehydrogenase
_xbiosynthesis
650 0 4 _aTime Factors
700 1 _aBzik, D J
700 1 _aHorii, T
773 0 _tMolecular and biochemical parasitology
_gvol. 26
_gno. 1-2
_gp. 121-34
856 4 0 _uhttps://doi.org/10.1016/0166-6851(87)90136-8
_zAvailable from publisher's website
999 _c3329656
_d3329656