| 000 | 01788 a2200505 4500 | ||
|---|---|---|---|
| 005 | 20250518100707.0 | ||
| 264 | 0 | _c20210512 | |
| 008 | 202105s 0 0 eng d | ||
| 022 | _a1464-3405 | ||
| 024 | 7 |
_a10.1016/j.bmcl.2020.127174 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aSteeneck, Christoph | |
| 245 | 0 | 0 |
_aDiscovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach. _h[electronic resource] |
| 260 |
_bBioorganic & medicinal chemistry letters _c06 2020 |
||
| 300 |
_a127174 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAdministration, Oral |
| 650 | 0 | 4 |
_aAmides _xadministration & dosage |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 | _aDrug Discovery |
| 650 | 0 | 4 |
_aMicrosomes, Liver _xchemistry |
| 650 | 0 | 4 | _aMolecular Structure |
| 650 | 0 | 4 |
_aNuclear Receptor Subfamily 1, Group F, Member 3 _xagonists |
| 650 | 0 | 4 |
_aOxadiazoles _xadministration & dosage |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 650 | 0 | 4 |
_aThiazoles _xadministration & dosage |
| 700 | 1 | _aGege, Christian | |
| 700 | 1 | _aKinzel, Olaf | |
| 700 | 1 | _aAlbers, Michael | |
| 700 | 1 | _aKleymann, Gerald | |
| 700 | 1 | _aSchlüter, Thomas | |
| 700 | 1 | _aSchulz, Andreas | |
| 700 | 1 | _aXue, Xiaohua | |
| 700 | 1 | _aCummings, Maxwell D | |
| 700 | 1 | _aFourie, Anne M | |
| 700 | 1 | _aLeonard, Kristi A | |
| 700 | 1 | _aScott, Brian | |
| 700 | 1 | _aEdwards, James P | |
| 700 | 1 | _aHoffmann, Thomas | |
| 700 | 1 | _aGoldberg, Steven D | |
| 773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 30 _gno. 12 _gp. 127174 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmcl.2020.127174 _zAvailable from publisher's website |
| 999 |
_c30901011 _d30901011 |
||