000 | 01895 a2200493 4500 | ||
---|---|---|---|
005 | 20250518095949.0 | ||
264 | 0 | _c20210614 | |
008 | 202106s 0 0 eng d | ||
022 | _a1860-7187 | ||
024 | 7 |
_a10.1002/cmdc.202000160 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aBehnisch-Cornwell, Steven | |
245 | 0 | 0 |
_aPentathiepins: A Novel Class of Glutathione Peroxidase 1 Inhibitors that Induce Oxidative Stress, Loss of Mitochondrial Membrane Potential and Apoptosis in Human Cancer Cells. _h[electronic resource] |
260 |
_bChemMedChem _c08 2020 |
||
300 |
_a1515-1528 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 |
_aAntineoplastic Agents _xchemical synthesis |
650 | 0 | 4 |
_aApoptosis _xdrug effects |
650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
650 | 0 | 4 |
_aCell Survival _xdrug effects |
650 | 0 | 4 | _aDose-Response Relationship, Drug |
650 | 0 | 4 | _aDrug Screening Assays, Antitumor |
650 | 0 | 4 |
_aEnzyme Inhibitors _xchemical synthesis |
650 | 0 | 4 |
_aGlutathione Peroxidase _xantagonists & inhibitors |
650 | 0 | 4 |
_aHeterocyclic Compounds _xchemical synthesis |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aMembrane Potential, Mitochondrial _xdrug effects |
650 | 0 | 4 | _aMolecular Structure |
650 | 0 | 4 |
_aOxidative Stress _xdrug effects |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 |
_aSulfides _xchemical synthesis |
650 | 0 | 4 | _aTumor Cells, Cultured |
650 | 0 | 4 | _aGlutathione Peroxidase GPX1 |
700 | 1 | _aBandaru, Siva Sankar Murthy | |
700 | 1 | _aNapierkowski, Martin | |
700 | 1 | _aWolff, Lisa | |
700 | 1 | _aZubair, Muhammad | |
700 | 1 | _aUrbainsky, Claudia | |
700 | 1 | _aLillig, Christopher | |
700 | 1 | _aSchulzke, Carola | |
700 | 1 | _aBednarski, Patrick J | |
773 | 0 |
_tChemMedChem _gvol. 15 _gno. 16 _gp. 1515-1528 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1002/cmdc.202000160 _zAvailable from publisher's website |
999 |
_c30877715 _d30877715 |