000			02041 a2200565 4500
005			20250518095812.0
264		0	_c20201201
008			202012s 0 0 eng d
022			_a1873-2968
024	7		_a10.1016/j.bcp.2020.113980 _2doi
040			_aNLM _beng _cNLM
100	1		_aBouknight, Kayla D
245	0	0	_aStructural and kinetic evidence of aging after organophosphate inhibition of human Cathepsin A. _h[electronic resource]
260			_bBiochemical pharmacology _c07 2020
300			_a113980 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650	0	4	_aAcetylcholinesterase _xchemistry
650	0	4	_aBinding Sites
650	0	4	_aCathepsin A _xantagonists & inhibitors
650	0	4	_aCell Line
650	0	4	_aChemical Warfare Agents _xchemistry
650	0	4	_aCholinesterase Inhibitors _xchemistry
650	0	4	_aCrystallography, X-Ray
650	0	4	_aGPI-Linked Proteins _xantagonists & inhibitors
650	0	4	_aGene Expression
650	0	4	_aHEK293 Cells
650	0	4	_aHumans
650	0	4	_aIsoflurophate _xchemistry
650	0	4	_aKinetics
650	0	4	_aModels, Molecular
650	0	4	_aOrganophosphorus Compounds _xchemistry
650	0	4	_aOrganothiophosphorus Compounds _xchemistry
650	0	4	_aProtein Binding
650	0	4	_aProtein Conformation, alpha-Helical
650	0	4	_aProtein Conformation, beta-Strand
650	0	4	_aProtein Interaction Domains and Motifs
650	0	4	_aRecombinant Proteins _xchemistry
650	0	4	_aSarin _xchemistry
650	0	4	_aSoman _xchemistry
650	0	4	_aSubstrate Specificity
650	0	4	_aTime Factors
700	1		_aJurkouich, Kayla M
700	1		_aCompton, Jaimee R
700	1		_aKhavrutskii, Ilja V
700	1		_aGuelta, Mark A
700	1		_aHarvey, Steven P
700	1		_aLegler, Patricia M
773	0		_tBiochemical pharmacology _gvol. 177 _gp. 113980
856	4	0	_uhttps://doi.org/10.1016/j.bcp.2020.113980 _zAvailable from publisher's website
999			_c30872242 _d30872242