000 01877 a2200565 4500
005 20250518095609.0
264 0 _c20201112
008 202011s 0 0 eng d
022 _a1520-4804
024 7 _a10.1021/acs.jmedchem.0c00278
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aŠála, Michal
245 0 0 _aNovel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer's Disease.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_c06 2020
300 _a6028-6056 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAlzheimer Disease
_xdrug therapy
650 0 4 _aAnimals
650 0 4 _aBody Weight
_xdrug effects
650 0 4 _aBrain
_xmetabolism
650 0 4 _aDisease Models, Animal
650 0 4 _aEnzyme Inhibitors
_xchemistry
650 0 4 _aExosomes
_xmetabolism
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Transgenic
650 0 4 _aPyridazines
_xchemistry
650 0 4 _aSphingomyelin Phosphodiesterase
_xantagonists & inhibitors
650 0 4 _aStructure-Activity Relationship
700 1 _aHollinger, Kristen R
700 1 _aThomas, Ajit G
700 1 _aDash, Ranjeet P
700 1 _aTallon, Carolyn
700 1 _aVeeravalli, Vijayabhaskar
700 1 _aLovell, Lyndah
700 1 _aKögler, Martin
700 1 _aHřebabecký, Hubert
700 1 _aProcházková, Eliška
700 1 _aNešuta, Ondřej
700 1 _aDonoghue, Amanda
700 1 _aLam, Jenny
700 1 _aRais, Rana
700 1 _aRojas, Camilo
700 1 _aSlusher, Barbara S
700 1 _aNencka, Radim
773 0 _tJournal of medicinal chemistry
_gvol. 63
_gno. 11
_gp. 6028-6056
856 4 0 _uhttps://doi.org/10.1021/acs.jmedchem.0c00278
_zAvailable from publisher's website
999 _c30865479
_d30865479