| 000 | 01586 a2200445 4500 | ||
|---|---|---|---|
| 005 | 20250518095149.0 | ||
| 264 | 0 | _c20201214 | |
| 008 | 202012s 0 0 eng d | ||
| 022 | _a2375-2548 | ||
| 024 | 7 |
_a10.1126/sciadv.aax0069 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aSarkar, Saswata S | |
| 245 | 0 | 0 |
_aThe hypertrophic cardiomyopathy mutations R403Q and R663H increase the number of myosin heads available to interact with actin. _h[electronic resource] |
| 260 |
_bScience advances _c04 2020 |
||
| 300 |
_aeaax0069 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aActins _xchemistry |
| 650 | 0 | 4 | _aAlleles |
| 650 | 0 | 4 | _aAmino Acid Substitution |
| 650 | 0 | 4 | _aBinding Sites |
| 650 | 0 | 4 |
_aCardiomyopathy, Hypertrophic _xgenetics |
| 650 | 0 | 4 | _aGenetic Predisposition to Disease |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aMutation |
| 650 | 0 | 4 |
_aMyocardial Contraction _xgenetics |
| 650 | 0 | 4 |
_aMyosins _xchemistry |
| 650 | 0 | 4 | _aProtein Binding |
| 650 | 0 | 4 | _aProtein Conformation |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 650 | 0 | 4 |
_aVentricular Myosins _xgenetics |
| 700 | 1 | _aTrivedi, Darshan V | |
| 700 | 1 | _aMorck, Makenna M | |
| 700 | 1 | _aAdhikari, Arjun S | |
| 700 | 1 | _aPasha, Shaik N | |
| 700 | 1 | _aRuppel, Kathleen M | |
| 700 | 1 | _aSpudich, James A | |
| 773 | 0 |
_tScience advances _gvol. 6 _gno. 14 _gp. eaax0069 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1126/sciadv.aax0069 _zAvailable from publisher's website |
| 999 |
_c30852105 _d30852105 |
||