000			02061 a2200613 4500
005			20250518095143.0
264		0	_c20201008
008			202010s 0 0 eng d
022			_a1552-4469
024	7		_a10.1038/s41589-020-0518-9 _2doi
040			_aNLM _beng _cNLM
100	1		_aMathony, Jan
245	0	0	_aComputational design of anti-CRISPR proteins with improved inhibition potency. _h[electronic resource]
260			_bNature chemical biology _cJul 2020
300			_a725-730 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAmino Acid Sequence
650	0	4	_aCRISPR-Associated Protein 9 _xgenetics
650	0	4	_aCRISPR-Cas Systems
650	0	4	_aCell Line, Tumor
650	0	4	_aClustered Regularly Interspaced Short Palindromic Repeats
650	0	4	_aGene Editing _xmethods
650	0	4	_aGenome, Human
650	0	4	_aHEK293 Cells
650	0	4	_aHepatocytes _xcytology
650	0	4	_aHumans
650	0	4	_aMicroRNAs _xgenetics
650	0	4	_aModels, Molecular
650	0	4	_aMutagenesis, Insertional
650	0	4	_aNeisseria meningitidis _xenzymology
650	0	4	_aPlasmids _xchemistry
650	0	4	_aProtein Domains
650	0	4	_aProtein Engineering _xmethods
650	0	4	_aProtein Structure, Secondary
650	0	4	_aRNA, Guide, CRISPR-Cas Systems _xgenetics
650	0	4	_aStaphylococcus aureus _xenzymology
700	1		_aHarteveld, Zander
700	1		_aSchmelas, Carolin
700	1		_aUpmeier Zu Belzen, Julius
700	1		_aAschenbrenner, Sabine
700	1		_aSun, Wei
700	1		_aHoffmann, Mareike D
700	1		_aStengl, Christina
700	1		_aScheck, Andreas
700	1		_aGeorgeon, Sandrine
700	1		_aRosset, Stéphane
700	1		_aWang, Yanli
700	1		_aGrimm, Dirk
700	1		_aEils, Roland
700	1		_aCorreia, Bruno E
700	1		_aNiopek, Dominik
773	0		_tNature chemical biology _gvol. 16 _gno. 7 _gp. 725-730
856	4	0	_uhttps://doi.org/10.1038/s41589-020-0518-9 _zAvailable from publisher's website
999			_c30851750 _d30851750