000 | 01607 a2200505 4500 | ||
---|---|---|---|
005 | 20250518095143.0 | ||
264 | 0 | _c20201007 | |
008 | 202010s 0 0 eng d | ||
022 | _a1546-1696 | ||
024 | 7 |
_a10.1038/s41587-020-0491-6 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aGaudelli, Nicole M | |
245 | 0 | 0 |
_aDirected evolution of adenine base editors with increased activity and therapeutic application. _h[electronic resource] |
260 |
_bNature biotechnology _c07 2020 |
||
300 |
_a892-900 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 |
_aAdenine _xmetabolism |
650 | 0 | 4 | _aAdenosine Deaminase |
650 | 0 | 4 |
_aCRISPR-Cas Systems _xgenetics |
650 | 0 | 4 |
_aCytosine _xmetabolism |
650 | 0 | 4 |
_aDNA _xgenetics |
650 | 0 | 4 |
_aGene Editing _xmethods |
650 | 0 | 4 | _aHEK293 Cells |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aMutation _xgenetics |
650 | 0 | 4 | _aRNA, Guide, CRISPR-Cas Systems |
700 | 1 | _aLam, Dieter K | |
700 | 1 | _aRees, Holly A | |
700 | 1 | _aSolá-Esteves, Noris M | |
700 | 1 | _aBarrera, Luis A | |
700 | 1 | _aBorn, David A | |
700 | 1 | _aEdwards, Aaron | |
700 | 1 | _aGehrke, Jason M | |
700 | 1 | _aLee, Seung-Joo | |
700 | 1 | _aLiquori, Alexander J | |
700 | 1 | _aMurray, Ryan | |
700 | 1 | _aPacker, Michael S | |
700 | 1 | _aRinaldi, Conrad | |
700 | 1 | _aSlaymaker, Ian M | |
700 | 1 | _aYen, Jonathan | |
700 | 1 | _aYoung, Lauren E | |
700 | 1 | _aCiaramella, Giuseppe | |
773 | 0 |
_tNature biotechnology _gvol. 38 _gno. 7 _gp. 892-900 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1038/s41587-020-0491-6 _zAvailable from publisher's website |
999 |
_c30851732 _d30851732 |