000 | 01732 a2200469 4500 | ||
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005 | 20250518094824.0 | ||
264 | 0 | _c20210430 | |
008 | 202104s 0 0 eng d | ||
022 | _a1464-3405 | ||
024 | 7 |
_a10.1016/j.bmcl.2020.127170 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aSatheeshkumar, Rajendran | |
245 | 0 | 0 |
_aSynthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors. _h[electronic resource] |
260 |
_bBioorganic & medicinal chemistry letters _c06 2020 |
||
300 |
_a127170 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 |
_aAmides _xchemistry |
650 | 0 | 4 | _aBinding Sites |
650 | 0 | 4 |
_aEnzyme Inhibitors _xchemical synthesis |
650 | 0 | 4 |
_aHeterocyclic Compounds _xchemistry |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aKinetics |
650 | 0 | 4 | _aMolecular Docking Simulation |
650 | 0 | 4 |
_aProtein Tyrosine Phosphatase, Non-Receptor Type 1 _xantagonists & inhibitors |
650 | 0 | 4 |
_aProtein Tyrosine Phosphatase, Non-Receptor Type 11 _xantagonists & inhibitors |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 | _asrc Homology Domains |
700 | 1 | _aZhu, Rui | |
700 | 1 | _aFeng, Bo | |
700 | 1 | _aHuang, Chao | |
700 | 1 | _aGao, Ya | |
700 | 1 | _aGao, Li-Xin | |
700 | 1 | _aShen, Chao | |
700 | 1 | _aHou, Ting-Jun | |
700 | 1 | _aXu, Lei | |
700 | 1 | _aLi, Jia | |
700 | 1 | _aZhu, Yun-Long | |
700 | 1 | _aZhou, Yu-Bo | |
700 | 1 | _aWang, Wen-Long | |
773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 30 _gno. 11 _gp. 127170 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmcl.2020.127170 _zAvailable from publisher's website |
999 |
_c30840496 _d30840496 |