000 01763 a2200457 4500
005 20250518093144.0
264 0 _c20200910
008 202009s 0 0 eng d
022 _a1521-0103
024 7 _a10.1124/jpet.119.264499
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aIida, Hiroyuki
245 0 0 _aPharmacokinetic-Pharmacodynamic-Efficacy Modeling of ONO-7579, a Novel Pan-Tropomyosin Receptor Kinase Inhibitor, in a Murine Xenograft Tumor Model.
_h[electronic resource]
260 _bThe Journal of pharmacology and experimental therapeutics
_c06 2020
300 _a361-369 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xpharmacokinetics
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aColorectal Neoplasms
_xdrug therapy
650 0 4 _aDisease Models, Animal
650 0 4 _aFemale
650 0 4 _aHeterografts
_xdrug effects
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aOrganic Chemicals
_xpharmacokinetics
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aProtein Kinase Inhibitors
_xpharmacokinetics
650 0 4 _aReceptor Protein-Tyrosine Kinases
_xantagonists & inhibitors
650 0 4 _aXenograft Model Antitumor Assays
_xmethods
700 1 _aFujikawa, Ryu
700 1 _aKozaki, Ryohei
700 1 _aHarada, Ryuichi
700 1 _aHosokawa, Yuya
700 1 _aOgawara, Ken-Ichi
700 1 _aOhno, Tomoya
773 0 _tThe Journal of pharmacology and experimental therapeutics
_gvol. 373
_gno. 3
_gp. 361-369
856 4 0 _uhttps://doi.org/10.1124/jpet.119.264499
_zAvailable from publisher's website
999 _c30785780
_d30785780