000 02063 a2200601 4500
005 20250518092942.0
264 0 _c20201211
008 202012s 0 0 eng d
022 _a2045-2322
024 7 _a10.1038/s41598-020-62192-8
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLi, Chunzhu
245 0 0 _aGluN2A-selective positive allosteric modulator-nalmefene-flumazenil reverses ketamine-fentanyl-dexmedetomidine-induced anesthesia and analgesia in rats.
_h[electronic resource]
260 _bScientific reports
_c03 2020
300 _a5265 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdjuvants, Anesthesia
650 0 4 _aAllosteric Regulation
650 0 4 _aAnalgesia
650 0 4 _aAnesthesia
650 0 4 _aAnimals
650 0 4 _aDelayed Emergence from Anesthesia
_xdrug therapy
650 0 4 _aDexmedetomidine
_xantagonists & inhibitors
650 0 4 _aDrug Combinations
650 0 4 _aDrug Evaluation, Preclinical
650 0 4 _aFemale
650 0 4 _aFentanyl
_xantagonists & inhibitors
650 0 4 _aFlumazenil
_xpharmacology
650 0 4 _aGABA-A Receptor Antagonists
_xpharmacology
650 0 4 _aKetamine
_xantagonists & inhibitors
650 0 4 _aMale
650 0 4 _aMaze Learning
_xdrug effects
650 0 4 _aNaltrexone
_xanalogs & derivatives
650 0 4 _aNarcotic Antagonists
_xpharmacology
650 0 4 _aNociception
_xdrug effects
650 0 4 _aPain Measurement
650 0 4 _aRats
650 0 4 _aReceptors, N-Methyl-D-Aspartate
_xagonists
650 0 4 _aReflex, Righting
_xdrug effects
650 0 4 _aRotarod Performance Test
700 1 _aYan, Jia
700 1 _aTang, Dewei
700 1 _aZhu, Jidong
700 1 _aHuang, Chen
700 1 _aSun, Yu
700 1 _aHu, Rong
700 1 _aWang, Hao
700 1 _aFu, Chaoying
700 1 _aChen, Yelin
700 1 _aJiang, Hong
773 0 _tScientific reports
_gvol. 10
_gno. 1
_gp. 5265
856 4 0 _uhttps://doi.org/10.1038/s41598-020-62192-8
_zAvailable from publisher's website
999 _c30778462
_d30778462