000 | 01641 a2200445 4500 | ||
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005 | 20250518092654.0 | ||
264 | 0 | _c20210224 | |
008 | 202102s 0 0 eng d | ||
022 | _a1090-2120 | ||
024 | 7 |
_a10.1016/j.bioorg.2020.103755 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aÁlvarez, Raquel | |
245 | 0 | 0 |
_aPotent colchicine-site ligands with improved intrinsic solubility by replacement of the 3,4,5-trimethoxyphenyl ring with a 2-methylsulfanyl-6-methoxypyridine ring. _h[electronic resource] |
260 |
_bBioorganic chemistry _c05 2020 |
||
300 |
_a103755 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 |
_aAntineoplastic Agents _xchemical synthesis |
650 | 0 | 4 |
_aCell Cycle _xdrug effects |
650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
650 | 0 | 4 |
_aColchicine _xchemical synthesis |
650 | 0 | 4 | _aDose-Response Relationship, Drug |
650 | 0 | 4 | _aDrug Screening Assays, Antitumor |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aLigands |
650 | 0 | 4 | _aMolecular Structure |
650 | 0 | 4 |
_aPolymerization _xdrug effects |
650 | 0 | 4 |
_aPyridines _xchemistry |
650 | 0 | 4 | _aSolubility |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 |
_aTubulin _xmetabolism |
650 | 0 | 4 | _aTumor Cells, Cultured |
700 | 1 | _aAramburu, Laura | |
700 | 1 | _aGajate, Consuelo | |
700 | 1 | _aVicente-Blázquez, Alba | |
700 | 1 | _aMollinedo, Faustino | |
700 | 1 | _aMedarde, Manuel | |
700 | 1 | _aPeláez, Rafael | |
773 | 0 |
_tBioorganic chemistry _gvol. 98 _gp. 103755 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bioorg.2020.103755 _zAvailable from publisher's website |
999 |
_c30768858 _d30768858 |