000 02452 a2200613 4500
005 20250518092154.0
264 0 _c20201228
008 202012s 0 0 eng d
022 _a1090-2104
024 7 _a10.1016/j.bbrc.2020.02.165
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aInoue, Chisato
245 0 0 _aInvolvement of MCL1, c-myc, and cyclin D2 protein degradation in ponatinib-induced cytotoxicity against T315I(+) Ph+leukemia cells.
_h[electronic resource]
260 _bBiochemical and biophysical research communications
_c05 2020
300 _a1074-1080 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aCell Death
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aCyclin D2
_xgenetics
650 0 4 _aDrug Resistance, Neoplasm
_xgenetics
650 0 4 _aDrug Synergism
650 0 4 _aGlycogen Synthase Kinase 3
_xantagonists & inhibitors
650 0 4 _aHumans
650 0 4 _aImatinib Mesylate
_xpharmacology
650 0 4 _aImidazoles
_xpharmacology
650 0 4 _aLeukemia, Myelogenous, Chronic, BCR-ABL Positive
_xdrug therapy
650 0 4 _aLeupeptins
_xpharmacology
650 0 4 _aMacrocyclic Compounds
_xpharmacology
650 0 4 _aMyeloid Cell Leukemia Sequence 1 Protein
_xantagonists & inhibitors
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aPhosphoinositide-3 Kinase Inhibitors
_xpharmacology
650 0 4 _aPhosphorylation
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aProtein Phosphatase 2
_xmetabolism
650 0 4 _aProteolysis
_xdrug effects
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xantagonists & inhibitors
650 0 4 _aProto-Oncogene Proteins c-myc
_xgenetics
650 0 4 _aPyridazines
_xpharmacology
650 0 4 _aPyrroles
_xpharmacology
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aWortmannin
_xpharmacology
700 1 _aSobue, Sayaka
700 1 _aKawamoto, Yoshiyuki
700 1 _aNishizawa, Yuji
700 1 _aIchihara, Masatoshi
700 1 _aAbe, Akihiro
700 1 _aHayakawa, Fumihiko
700 1 _aSuzuki, Motoshi
700 1 _aNozawa, Yoshinori
700 1 _aMurate, Takahsi
773 0 _tBiochemical and biophysical research communications
_gvol. 525
_gno. 4
_gp. 1074-1080
856 4 0 _uhttps://doi.org/10.1016/j.bbrc.2020.02.165
_zAvailable from publisher's website
999 _c30752776
_d30752776