000 01899 a2200505 4500
005 20250518091528.0
264 0 _c20210430
008 202104s 0 0 eng d
022 _a1573-8744
024 7 _a10.1007/s10928-020-09680-6
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aChen, Wenbo
245 0 0 _aA physiological model of granulopoiesis to predict clinical drug induced neutropenia from in vitro bone marrow studies: with application to a cell cycle inhibitor.
_h[electronic resource]
260 _bJournal of pharmacokinetics and pharmacodynamics
_c04 2020
300 _a163-182 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAlgorithms
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aBone Marrow
_xdrug effects
650 0 4 _aCell Cycle
_xdrug effects
650 0 4 _aCell Movement
650 0 4 _aFilgrastim
_xpharmacology
650 0 4 _aGranulocyte Colony-Stimulating Factor
_xpharmacology
650 0 4 _aGranulocytes
_xdrug effects
650 0 4 _aHematopoiesis
_xdrug effects
650 0 4 _aHumans
650 0 4 _aLeukocyte Count
650 0 4 _aModels, Biological
650 0 4 _aNeutropenia
_xchemically induced
650 0 4 _aNeutrophils
_xdrug effects
650 0 4 _aPiperazines
_xpharmacology
650 0 4 _aPolyethylene Glycols
_xpharmacology
650 0 4 _aPyridines
_xpharmacology
650 0 4 _aStem Cells
_xdrug effects
700 1 _aBoras, Britton
700 1 _aSung, Tae
700 1 _aYu, Yanke
700 1 _aZheng, Jenny
700 1 _aWang, Diane
700 1 _aHu, Wenyue
700 1 _aSpilker, Mary E
700 1 _aD'Argenio, David Z
773 0 _tJournal of pharmacokinetics and pharmacodynamics
_gvol. 47
_gno. 2
_gp. 163-182
856 4 0 _uhttps://doi.org/10.1007/s10928-020-09680-6
_zAvailable from publisher's website
999 _c30732526
_d30732526