000 01983 a2200589 4500
005 20250518085320.0
264 0 _c20201112
008 202011s 0 0 eng d
022 _a2045-2322
024 7 _a10.1038/s41598-020-58366-z
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWang, Yudong
245 0 0 _aPhase I studies of vorinostat with ixazomib or pazopanib imply a role of antiangiogenesis-based therapy for TP53 mutant malignancies.
_h[electronic resource]
260 _bScientific reports
_c02 2020
300 _a3080 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAngiogenesis Inhibitors
_xadverse effects
650 0 4 _aBoron Compounds
_xadverse effects
650 0 4 _aGlycine
_xadverse effects
650 0 4 _aHumans
650 0 4 _aIndazoles
650 0 4 _aKaplan-Meier Estimate
650 0 4 _aMiddle Aged
650 0 4 _aMutation
_xgenetics
650 0 4 _aNeoplasms
_xdrug therapy
650 0 4 _aProgression-Free Survival
650 0 4 _aPyrimidines
_xadverse effects
650 0 4 _aSulfonamides
_xadverse effects
650 0 4 _aTreatment Outcome
650 0 4 _aTumor Suppressor Protein p53
_xgenetics
650 0 4 _aVorinostat
_xadverse effects
650 0 4 _aYoung Adult
700 1 _aJanku, Filip
700 1 _aPiha-Paul, Sarina
700 1 _aHess, Kenneth
700 1 _aBroaddus, Russell
700 1 _aLiu, Lidong
700 1 _aShi, Naiyi
700 1 _aOverman, Michael
700 1 _aKopetz, Scott
700 1 _aSubbiah, Vivek
700 1 _aNaing, Aung
700 1 _aHong, David
700 1 _aTsimberidou, Apostolia M
700 1 _aKarp, Daniel
700 1 _aYao, James
700 1 _aFu, Siqing
773 0 _tScientific reports
_gvol. 10
_gno. 1
_gp. 3080
856 4 0 _uhttps://doi.org/10.1038/s41598-020-58366-z
_zAvailable from publisher's website
999 _c30656247
_d30656247