000 01930 a2200565 4500
005 20250518085241.0
264 0 _c20210601
008 202106s 0 0 eng d
022 _a1096-0929
024 7 _a10.1093/toxsci/kfaa024
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMitra, Mayur S
245 0 0 _aA Potent Pan-TGFβ Neutralizing Monoclonal Antibody Elicits Cardiovascular Toxicity in Mice and Cynomolgus Monkeys.
_h[electronic resource]
260 _bToxicological sciences : an official journal of the Society of Toxicology
_c05 2020
300 _a24-34 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aAntibodies, Monoclonal, Humanized
_xblood
650 0 4 _aAntibodies, Neutralizing
_xblood
650 0 4 _aCardiotoxicity
650 0 4 _aCardiovascular Diseases
_xchemically induced
650 0 4 _aCell Line
650 0 4 _aFemale
650 0 4 _aHeart
_xdrug effects
650 0 4 _aHemorrhage
_xchemically induced
650 0 4 _aHumans
650 0 4 _aMacaca fascicularis
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMyocardium
_xmetabolism
650 0 4 _aRisk Assessment
650 0 4 _aTime Factors
650 0 4 _aToxicity Tests
650 0 4 _aToxicokinetics
650 0 4 _aTransforming Growth Factor beta
_xantagonists & inhibitors
700 1 _aLancaster, Karla
700 1 _aAdedeji, Adeyemi O
700 1 _aPalanisamy, Gopinath S
700 1 _aDave, Rutwij A
700 1 _aZhong, Fiona
700 1 _aHoldren, Matthew S
700 1 _aTurley, Shannon J
700 1 _aLiang, Wei-Ching
700 1 _aWu, Yan
700 1 _aMeng, Y Gloria
700 1 _aVernes, Jean-Michel
700 1 _aSchutten, Melissa M
773 0 _tToxicological sciences : an official journal of the Society of Toxicology
_gvol. 175
_gno. 1
_gp. 24-34
856 4 0 _uhttps://doi.org/10.1093/toxsci/kfaa024
_zAvailable from publisher's website
999 _c30654064
_d30654064