000 | 01359 a2200409 4500 | ||
---|---|---|---|
005 | 20250518085219.0 | ||
264 | 0 | _c20201021 | |
008 | 202010s 0 0 eng d | ||
022 | _a2375-2548 | ||
024 | 7 |
_a10.1126/sciadv.aay0187 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aAschenbrenner, Sabine | |
245 | 0 | 0 |
_aCoupling Cas9 to artificial inhibitory domains enhances CRISPR-Cas9 target specificity. _h[electronic resource] |
260 |
_bScience advances _c02 2020 |
||
300 |
_aeaay0187 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 |
_aCRISPR-Associated Protein 9 _xchemistry |
650 | 0 | 4 | _aCRISPR-Cas Systems |
650 | 0 | 4 | _aCell Line |
650 | 0 | 4 | _aEnzyme Activation |
650 | 0 | 4 | _aGene Editing |
650 | 0 | 4 |
_aGene Targeting _xmethods |
650 | 0 | 4 | _aGenes, Reporter |
650 | 0 | 4 | _aGenetic Loci |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aKinetics |
650 | 0 | 4 | _aModels, Theoretical |
650 | 0 | 4 | _aRecombinant Fusion Proteins |
650 | 0 | 4 | _aSubstrate Specificity |
700 | 1 | _aKallenberger, Stefan M | |
700 | 1 | _aHoffmann, Mareike D | |
700 | 1 | _aHuck, Adrian | |
700 | 1 | _aEils, Roland | |
700 | 1 | _aNiopek, Dominik | |
773 | 0 |
_tScience advances _gvol. 6 _gno. 6 _gp. eaay0187 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1126/sciadv.aay0187 _zAvailable from publisher's website |
999 |
_c30652783 _d30652783 |