| 000 | 01568 a2200409 4500 | ||
|---|---|---|---|
| 005 | 20250518083920.0 | ||
| 264 | 0 | _c20210224 | |
| 008 | 202102s 0 0 eng d | ||
| 022 | _a1090-2120 | ||
| 024 | 7 |
_a10.1016/j.bioorg.2020.103616 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aEl Ashry, El Sayed Helmy | |
| 245 | 0 | 0 |
_aStructure-based design and optimization of pyrimidine- and 1,2,4-triazolo[4,3-a]pyrimidine-based matrix metalloproteinase-10/13 inhibitors via Dimroth rearrangement towards targeted polypharmacology. _h[electronic resource] |
| 260 |
_bBioorganic chemistry _c03 2020 |
||
| 300 |
_a103616 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aCell Line, Tumor |
| 650 | 0 | 4 | _aDrug Design |
| 650 | 0 | 4 | _aDrug Screening Assays, Antitumor |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aMatrix Metalloproteinase 10 _xmetabolism |
| 650 | 0 | 4 |
_aMatrix Metalloproteinase 13 _xmetabolism |
| 650 | 0 | 4 |
_aMatrix Metalloproteinase Inhibitors _xchemistry |
| 650 | 0 | 4 | _aMolecular Docking Simulation |
| 650 | 0 | 4 |
_aNeoplasms _xdrug therapy |
| 650 | 0 | 4 | _aPolypharmacology |
| 650 | 0 | 4 |
_aPyridines _xchemistry |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 650 | 0 | 4 |
_aTriazoles _xchemistry |
| 700 | 1 | _aAwad, Laila Fathy | |
| 700 | 1 | _aTeleb, Mohamed | |
| 700 | 1 | _aIbrahim, Nihal Ahmed | |
| 700 | 1 | _aAbu-Serie, Marwa M | |
| 700 | 1 | _aAbd Al Moaty, Mohamed Nabil | |
| 773 | 0 |
_tBioorganic chemistry _gvol. 96 _gp. 103616 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bioorg.2020.103616 _zAvailable from publisher's website |
| 999 |
_c30609739 _d30609739 |
||