000 02175 a2200649 4500
005 20250518083825.0
264 0 _c20200416
008 202004s 0 0 eng d
022 _a1095-9203
024 7 _a10.1126/science.aaw3242
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWilmes, Stephan
245 0 0 _aMechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations.
_h[electronic resource]
260 _bScience (New York, N.Y.)
_c02 2020
300 _a643-652 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAmino Acid Substitution
_xgenetics
650 0 4 _aCarcinogenesis
_xgenetics
650 0 4 _aCell Membrane
_xchemistry
650 0 4 _aHeLa Cells
650 0 4 _aHumans
650 0 4 _aJanus Kinase 2
_xantagonists & inhibitors
650 0 4 _aLigands
650 0 4 _aMicroscopy, Fluorescence
650 0 4 _aModels, Molecular
650 0 4 _aMutation
650 0 4 _aNitriles
650 0 4 _aPhenylalanine
_xgenetics
650 0 4 _aProtein Multimerization
650 0 4 _aPyrazoles
_xpharmacology
650 0 4 _aPyrimidines
650 0 4 _aReceptors, Erythropoietin
_xchemistry
650 0 4 _aReceptors, Somatotropin
_xchemistry
650 0 4 _aReceptors, Thrombopoietin
_xchemistry
650 0 4 _aSignal Transduction
650 0 4 _aSingle Molecule Imaging
650 0 4 _aValine
_xgenetics
700 1 _aHafer, Maximillian
700 1 _aVuorio, Joni
700 1 _aTucker, Julie A
700 1 _aWinkelmann, Hauke
700 1 _aLöchte, Sara
700 1 _aStanly, Tess A
700 1 _aPulgar Prieto, Katiuska D
700 1 _aPoojari, Chetan
700 1 _aSharma, Vivek
700 1 _aRichter, Christian P
700 1 _aKurre, Rainer
700 1 _aHubbard, Stevan R
700 1 _aGarcia, K Christopher
700 1 _aMoraga, Ignacio
700 1 _aVattulainen, Ilpo
700 1 _aHitchcock, Ian S
700 1 _aPiehler, Jacob
773 0 _tScience (New York, N.Y.)
_gvol. 367
_gno. 6478
_gp. 643-652
856 4 0 _uhttps://doi.org/10.1126/science.aaw3242
_zAvailable from publisher's website
999 _c30606579
_d30606579