| 000 | 02463 a2200673 4500 | ||
|---|---|---|---|
| 005 | 20250518082208.0 | ||
| 264 | 0 | _c20201007 | |
| 008 | 202010s 0 0 eng d | ||
| 022 | _a1476-5551 | ||
| 024 | 7 |
_a10.1038/s41375-020-0714-3 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aQuijada-Álamo, Miguel | |
| 245 | 0 | 0 |
_aCRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition. _h[electronic resource] |
| 260 |
_bLeukemia _c06 2020 |
||
| 300 |
_a1599-1612 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aAdenine _xanalogs & derivatives |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAntineoplastic Combined Chemotherapy Protocols _xpharmacology |
| 650 | 0 | 4 |
_aAtaxia Telangiectasia Mutated Proteins _xgenetics |
| 650 | 0 | 4 | _aCRISPR-Cas Systems |
| 650 | 0 | 4 | _aCell Line, Tumor |
| 650 | 0 | 4 | _aChromosome Deletion |
| 650 | 0 | 4 |
_aChromosomes, Human, Pair 11 _xgenetics |
| 650 | 0 | 4 | _aDrug Synergism |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aLeukemia, Lymphocytic, Chronic, B-Cell _xgenetics |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 |
_aMutagenesis, Site-Directed _xmethods |
| 650 | 0 | 4 | _aMutation |
| 650 | 0 | 4 |
_aPhthalazines _xpharmacology |
| 650 | 0 | 4 |
_aPiperazines _xpharmacology |
| 650 | 0 | 4 | _aPiperidines |
| 650 | 0 | 4 |
_aPoly (ADP-Ribose) Polymerase-1 _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aPoly(ADP-ribose) Polymerase Inhibitors _xpharmacology |
| 650 | 0 | 4 |
_aProto-Oncogene Proteins c-bcr _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aPyrazoles _xpharmacology |
| 650 | 0 | 4 |
_aPyrimidines _xpharmacology |
| 650 | 0 | 4 | _aXenograft Model Antitumor Assays |
| 700 | 1 | _aHernández-Sánchez, María | |
| 700 | 1 | _aAlonso-Pérez, Verónica | |
| 700 | 1 | _aRodríguez-Vicente, Ana E | |
| 700 | 1 | _aGarcía-Tuñón, Ignacio | |
| 700 | 1 | _aMartín-Izquierdo, Marta | |
| 700 | 1 | _aHernández-Sánchez, Jesús María | |
| 700 | 1 | _aHerrero, Ana B | |
| 700 | 1 | _aBastida, José María | |
| 700 | 1 | _aSan Segundo, Laura | |
| 700 | 1 | _aGruber, Michaela | |
| 700 | 1 | _aGarcía, Juan Luis | |
| 700 | 1 | _aYin, Shanye | |
| 700 | 1 | _aTen Hacken, Elisa | |
| 700 | 1 | _aBenito, Rocío | |
| 700 | 1 | _aOrdóñez, José Luis | |
| 700 | 1 | _aWu, Catherine J | |
| 700 | 1 | _aHernández-Rivas, Jesús María | |
| 773 | 0 |
_tLeukemia _gvol. 34 _gno. 6 _gp. 1599-1612 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1038/s41375-020-0714-3 _zAvailable from publisher's website |
| 999 |
_c30553905 _d30553905 |
||