000 01685 a2200445 4500
005 20250518081700.0
264 0 _c20210602
008 202106s 0 0 eng d
022 _a1521-009X
024 7 _a10.1124/dmd.119.089326
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBreysse, Daniel H
245 0 0 _aCarbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified.
_h[electronic resource]
260 _bDrug metabolism and disposition: the biological fate of chemicals
_c03 2020
300 _a187-197 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAlcohol Oxidoreductases
_xmetabolism
650 0 4 _aAnimals
650 0 4 _aCardiotoxicity
_xmetabolism
650 0 4 _aCytosol
_xmetabolism
650 0 4 _aDoxorubicin
_xmetabolism
650 0 4 _aFemale
650 0 4 _aLiver
_xmetabolism
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Knockout
650 0 4 _aNADP
_xmetabolism
650 0 4 _aOxidation-Reduction
700 1 _aBoone, Ryan M
700 1 _aLong, Cameron M
700 1 _aMerrill, Miranda E
700 1 _aSchaupp, Christopher M
700 1 _aWhite, Collin C
700 1 _aKavanagh, Terrance J
700 1 _aSchmidt, Edward E
700 1 _aMerrill, Gary F
773 0 _tDrug metabolism and disposition: the biological fate of chemicals
_gvol. 48
_gno. 3
_gp. 187-197
856 4 0 _uhttps://doi.org/10.1124/dmd.119.089326
_zAvailable from publisher's website
999 _c30535584
_d30535584