000 01958 a2200541 4500
005 20250518080811.0
264 0 _c20210114
008 202101s 0 0 eng d
022 _a2041-4889
024 7 _a10.1038/s41419-019-2212-y
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aThatikonda, Sowjanya
245 0 0 _aPiperlongumine regulates epigenetic modulation and alleviates psoriasis-like skin inflammation via inhibition of hyperproliferation and inflammation.
_h[electronic resource]
260 _bCell death & disease
_c01 2020
300 _a21 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aChemokines
_xmetabolism
650 0 4 _aDioxolanes
_xpharmacology
650 0 4 _aEpidermis
_xpathology
650 0 4 _aEpigenesis, Genetic
_xdrug effects
650 0 4 _aHaCaT Cells
650 0 4 _aHistone Deacetylase Inhibitors
_xpharmacology
650 0 4 _aHistone Deacetylases
_xmetabolism
650 0 4 _aHistones
_xmetabolism
650 0 4 _aHumans
650 0 4 _aImiquimod
_xadverse effects
650 0 4 _aInflammation
_xdrug therapy
650 0 4 _aKeratin-17
_xmetabolism
650 0 4 _aKeratinocytes
_xdrug effects
650 0 4 _aLipopolysaccharides
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aModels, Biological
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aProtein Binding
_xdrug effects
650 0 4 _aPsoriasis
_xchemically induced
650 0 4 _aRAW 264.7 Cells
650 0 4 _aSTAT3 Transcription Factor
_xmetabolism
650 0 4 _aSkin
_xpathology
700 1 _aPooladanda, Venkatesh
700 1 _aSigalapalli, Dilep Kumar
700 1 _aGodugu, Chandraiah
773 0 _tCell death & disease
_gvol. 11
_gno. 1
_gp. 21
856 4 0 _uhttps://doi.org/10.1038/s41419-019-2212-y
_zAvailable from publisher's website
999 _c30506308
_d30506308