000 | 02260 a2200649 4500 | ||
---|---|---|---|
005 | 20250518074400.0 | ||
264 | 0 | _c20200817 | |
008 | 202008s 0 0 eng d | ||
022 | _a1755-4349 | ||
024 | 7 |
_a10.1038/s41557-019-0378-7 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aLe, Philipp | |
245 | 0 | 0 |
_aRepurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms. _h[electronic resource] |
260 |
_bNature chemistry _c02 2020 |
||
300 |
_a145-158 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. | ||
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAnti-Bacterial Agents _xchemical synthesis |
650 | 0 | 4 |
_aAutolysis _xchemically induced |
650 | 0 | 4 |
_aBenzodioxoles _xchemical synthesis |
650 | 0 | 4 |
_aBiofilms _xdrug effects |
650 | 0 | 4 | _aCell Line, Tumor |
650 | 0 | 4 | _aDrug Repositioning |
650 | 0 | 4 | _aFemale |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aMale |
650 | 0 | 4 |
_aMethicillin-Resistant Staphylococcus aureus _xdrug effects |
650 | 0 | 4 | _aMice, Inbred C57BL |
650 | 0 | 4 | _aMicrobial Sensitivity Tests |
650 | 0 | 4 | _aMolecular Dynamics Simulation |
650 | 0 | 4 | _aMolecular Structure |
650 | 0 | 4 |
_aProtein Kinase Inhibitors _xchemistry |
650 | 0 | 4 |
_aSorafenib _xanalogs & derivatives |
650 | 0 | 4 | _aStructure-Activity Relationship |
700 | 1 | _aKunold, Elena | |
700 | 1 | _aMacsics, Robert | |
700 | 1 | _aRox, Katharina | |
700 | 1 | _aJennings, Megan C | |
700 | 1 | _aUgur, Ilke | |
700 | 1 | _aReinecke, Maria | |
700 | 1 | _aChaves-Moreno, Diego | |
700 | 1 | _aHackl, Mathias W | |
700 | 1 | _aFetzer, Christian | |
700 | 1 | _aMandl, Franziska A M | |
700 | 1 | _aLehmann, Johannes | |
700 | 1 | _aKorotkov, Vadim S | |
700 | 1 | _aHacker, Stephan M | |
700 | 1 | _aKuster, Bernhard | |
700 | 1 | _aAntes, Iris | |
700 | 1 | _aPieper, Dietmar H | |
700 | 1 | _aRohde, Manfred | |
700 | 1 | _aWuest, William M | |
700 | 1 | _aMedina, Eva | |
700 | 1 | _aSieber, Stephan A | |
773 | 0 |
_tNature chemistry _gvol. 12 _gno. 2 _gp. 145-158 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1038/s41557-019-0378-7 _zAvailable from publisher's website |
999 |
_c30427586 _d30427586 |