000 02245 a2200685 4500
005 20250518074307.0
264 0 _c20200909
008 202009s 0 0 eng d
022 _a1540-9538
024 7 _a10.1084/jem.20191336
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLau, Anthony
245 0 0 _aActivated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production.
_h[electronic resource]
260 _bThe Journal of experimental medicine
_c02 2020
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntibody Formation
_xgenetics
650 0 4 _aAutoantibodies
_xblood
650 0 4 _aAutoantigens
_ximmunology
650 0 4 _aAutoimmunity
_xgenetics
650 0 4 _aClass I Phosphatidylinositol 3-Kinases
_xblood
650 0 4 _aFemale
650 0 4 _aGain of Function Mutation
650 0 4 _aGerminal Center
_ximmunology
650 0 4 _aHumans
650 0 4 _aImmune Tolerance
_ximmunology
650 0 4 _aImmunoglobulin M
_xblood
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Transgenic
650 0 4 _aPlasma Cells
_ximmunology
650 0 4 _aSignal Transduction
_xgenetics
700 1 _aAvery, Danielle T
700 1 _aJackson, Katherine
700 1 _aLenthall, Helen
700 1 _aVolpi, Stefano
700 1 _aBrigden, Henry
700 1 _aRussell, Amanda J
700 1 _aBier, Julia
700 1 _aReed, Joanne H
700 1 _aSmart, Joanne M
700 1 _aCole, Theresa
700 1 _aChoo, Sharon
700 1 _aGray, Paul E
700 1 _aBerglund, Lucinda J
700 1 _aHsu, Peter
700 1 _aWong, Melanie
700 1 _aO'Sullivan, Michael
700 1 _aBoztug, Kaan
700 1 _aMeyts, Isabelle
700 1 _aUzel, Gulbu
700 1 _aNotarangelo, Luigi D
700 1 _aBrink, Robert
700 1 _aGoodnow, Christopher C
700 1 _aTangye, Stuart G
700 1 _aDeenick, Elissa K
773 0 _tThe Journal of experimental medicine
_gvol. 217
_gno. 2
856 4 0 _uhttps://doi.org/10.1084/jem.20191336
_zAvailable from publisher's website
999 _c30424577
_d30424577